Checks liver fat in adults born with low birth weight
Studies liver fat in adults aged 34 to 49 born with low birth weight.
Plain-language title generated from the registry record
Registry title: Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals
Key facts
- Where
- Herlev, DenmarkSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for healthy men and women born at full term. 250 had a low birth weight and 50 had a normal birth weight. It studies the risk of fatty liver disease.
- Age
- 34 Years to 49 Years
- Sex
- Men and women
- Disease stage
- Healthy people without known metabolic or liver disease.
- Biomarker or test result
- Birth weight below the 10th percentile of the population (low birth weight group), or between 50-90% of the population (normal birth weight group). Born in weeks 39-41.
Main reasons for not taking part
- BMI above 35 kg/m2
- Disease or medication known to affect the main outcome
- Self-reported high physical activity level
- Alcohol intake above general recommendations
- Weight gain or loss of more than 3 kg (7 lb) in the past 6 months
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 34 and 49 years old?
Source: NCT05890365, who can take part
Where in Denmark
- Steno Diabetes Center CopenhagenHerlev, DenmarkContact: Charlotte Brøns, PhdTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Steno Diabetes Center Copenhagen
- Trial code
- NCT05890365
- Record updated
- 11 June 2026
- Original description
The investigators recently demonstrated a increase in liver fat in early middle-aged LBW compared to normal birth weight (NBW) men, and 20% of the LBW - but none of the normal birth weight (NBW) - men had previously unknown non-alcoholic fatty liver disease (NAFLD). Here the investigators will further examine the Increased risk of non-alcoholic fatty liver disease in low birth weight individuals by performing a validation study.Read full original descriptionShow less
Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals - Extended Validation.
The investigators recently demonstrated a increase in liver fat in early middle-aged LBW compared to normal birth weight (NBW) men, and 20% of the LBW - but none of the normal birth weight (NBW) - men had previously unknown non-alcoholic fatty liver disease (NAFLD). Here the investigators will further examine the Increased risk of non-alcoholic fatty liver disease in low birth weight individuals by performing a validation study.
Inclusion: 250 healthy, men and women born with a low birth weight (birth weight (BW) <10% of the population) and 50 born with a normal birth weight controls (BW between 50-90% of the population); born at term (weeks 39-41).
Exclusion: Disease/medication known to affect primary outcome; Metabolic/liver disease; BMI>35 kg/m2; Self-reported high physical activity level; Alcohol intake above general recommendations; Weight gain/loss of >3 kg within the past 6 months.