Brain PERfusion Evaluation by Contrast-Enhanced UltraSound
Key facts
- Where
- Paris, FranceSee the site
Where in France
- Lariboisière HospitalParis, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT05893407
- Record updated
- 19 June 2025
- Original description
The objective of the study is to assess brain tissue perfusion by contrast-enhanced ultrasound perfusion imaging (PerCEUS) in acute brain injuries. More precisely, it aims :Read full original descriptionShow less
Quantification of Cerebral Perfusion at the Patient's Bedside When Performing Contrast-enhanced Ultrasound in Neurointensive Care Patients
The objective of the study is to assess brain tissue perfusion by contrast-enhanced ultrasound perfusion imaging (PerCEUS) in acute brain injuries. More precisely, it aims :
* to evaluate the heterogeneity of brain perfusion and thus diagnose brain tissue hypoperfusion with contrast-enhanced ultrasound. * to correlate contrast-enhanced ultrasound with perfusion measurements by usual multimodal monitoring.
Inclusion: Age ≥18; Intensive care unit admission for acute brain injury; Proven acute brain injury by CT and/or MRI; Requiring a contrast ultrasound imaging; Informed consent of patient or relative.
Exclusion: Contraindications to Sonovue ® : acute coronary syndromes, severe ischemic heart disease (requiring revascularization), pulmonary arterial hypertension > 90 mmHg, right-left shunt, ARDS, dobutamine's use, known allergy or adverse reaction to Sonovue®; Pregnancy; Not sufficient temporal window; Patient on State Medical Assistance.