NCT05903001Recruiting
Diaphragmatic Function as a Biomarker
Diaphragmatic Function as a Biomarker in Patients With Respiratory Diseases
Source: ClinicalTrials.gov · Last updated 28 Jan 2026
Brief summary (registry, in English)
Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory diseases are still poorly understood. Diaphragm dysfunction might be highly prevalent in patients with dyspnea and respiratory diseases. The association of diaphragm function and potential prognostic significance in patients with respiratory diseases has not yet been investigated.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 800 (estimated)
- First submitted
- 18 May 2023
- Start date
- 1 Jul 2023
- Primary completion date
- 30 Dec 2026
- Lead sponsor
- RWTH Aachen University
- NCT number
- NCT05903001
What you commit to
- Study type: Observational
- Planned participants: 800
- From 1 Jul 2023 to the primary completion date, 30 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- alcohol or drug abuse
- emergency inpatient hospital stay within 4 weeks before study-specific examinations
Other illness
- current or treatments or diseases in the past which could influence the evaluation of the study
- epilepsy
Other
- BMI \> 35
- Expected lack of willingness to actively participate in study-related measures
- disc herniation/prolapse
- wheelchair bound
- in custody due to an official or court order
- in a dependent relationship or employment relationship with investigating physician or one of their deputy
Who the study is looking for
- patient has one of the following lung diseases: COPD, bronchial asthma, pulmonary fibrosis, pulmonary hypertension
- is 18 years or older
- is mentally and physically able to understand the study and to follow instructions
- are legally competent
- signed declaration of consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| RWTH Aachen University Hospital Coordinator of this site? Confirm its status | Aachen | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.