Diaphragm Function Measured in People With Lung Diseases
Studies diaphragm muscle function in adults with breathing-related lung diseases such as asthma and COPD.
Plain-language title generated from the registry record
Registry title: Diaphragmatic Function as a Biomarker
Key facts
- Where
- Aachen, GermanySee the site
Where in Germany
- RWTH Aachen University HospitalAachen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- RWTH Aachen University
- Trial code
- NCT05903001
- Record updated
- 28 January 2026
- Original description
Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory diseases are still poorly understood. Diaphragm dysfunction might be highly prevalent in patients with dyspnea and respiratory diseases. The association of diaphragm function and potential prognostic significance in patients with respiratory diseases has not yet been investigated.Read full original descriptionShow less
Diaphragmatic Function as a Biomarker in Patients With Respiratory Diseases
Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory diseases are still poorly understood. Diaphragm dysfunction might be highly prevalent in patients with dyspnea and respiratory diseases. The association of diaphragm function and potential prognostic significance in patients with respiratory diseases has not yet been investigated.
Inclusion: patient has one of the following lung diseases: COPD, bronchial asthma, pulmonary fibrosis, pulmonary hypertension; is 18 years or older; is mentally and physically able to understand the study and to follow instructions; are legally competent; signed declaration of consent.
Exclusion: alcohol or drug abuse; emergency inpatient hospital stay within 4 weeks before study-specific examinations; current or treatments or diseases in the past which could influence the evaluation of the study; epilepsy; BMI > 35; Expected lack of willingness to actively participate in study-related measures; disc herniation/prolapse; wheelchair bound; in custody due to an official or court order; in a dependent relationship or employment relationship with investigating physician or one of their deputy.