Observational study following bone health and fracture risk in Chinese adults
Studies how well a fracture risk tool predicts bone breaks in people with osteoporosis.
Plain-language title generated from the registry record
Registry title: Health ImprOvement Program of Bone in China
Key facts
- Where
- Changsha, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults over 40 who had a dual-energy X-ray bone density scan at the health management center of the hospital.
- Age
- 40 to 100 years
- Sex
- All sexes
- Earlier treatment
- People who were treated with effective anti-osteoporosis drugs cannot join.
- Biomarker or test result
- Had a dual-energy X-ray bone mineral density measurement.
Main reasons for not taking part
- Under 40 years of age
- Had hip replacement or lumbar surgery and cannot have the bone density scan
- Treated with effective anti-osteoporosis drugs
- History of malignant tumors
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 100 years old?
Source: NCT05906147, who can take part
Where in China
- Health Management Center, The Second Xiangya Hospital of Central South UniversityChangsha, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Second Xiangya Hospital of Central South University
- Trial code
- NCT05906147
- Record updated
- 15 June 2023
- Original description
Fracture risk factors have long been identified as key factors in osteoporosis and fragility fractures. The WHO recommended Fracture risk assessmenttool (FRAX) applies clinical risk factors to assess the absolute risk of osteoporotic fractures in each individual. Our preliminary study suggests that FRAX estimates may underestimate the risk of fractures in the Chinese population. In order to optimize the risk prediction model of osteoporotic fractures, a treatment threshold and its optimal cutting point were initially established based on the data of the health management Center of the Second Xiangya Hospital of Central South University.Read full original descriptionShow less
Health ImprOvement Program of Bone in China
Fracture risk factors have long been identified as key factors in osteoporosis and fragility fractures. The WHO recommended Fracture risk assessmenttool (FRAX) applies clinical risk factors to assess the absolute risk of osteoporotic fractures in each individual. Our preliminary study suggests that FRAX estimates may underestimate the risk of fractures in the Chinese population. In order to optimize the risk prediction model of osteoporotic fractures, a treatment threshold and its optimal cutting point were initially established based on the data of the health management Center of the Second Xiangya Hospital of Central South University.
Inclusion: Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old. Have independent civil capacity and agree to participate, and sign informed consent.
Exclusion: Under 40 years of age， Patients who had undergone hip replacement or lumbar surgery and could not perform dual-energy X-ray BMD testing; Patients who have been treated with effective anti-osteoporosis drugs or have a history of malignant tumors.