Effects of rTMS on Food Choice in Anorexia Nervosa
Key facts
- Who runs it
- New York State Psychiatric Institute
- Where
- New York, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 72 people, planned
- Started
- 24 Apr 2023
- Expected to end
- 30 Jun 2027
- Type of study
- Interventional, 2 groupsOne group gets a sham (pretend) treatment, for comparison.
- Treatments tested
- High-frequency repetitive transcranial magnetic stimulation (active rTMS)
- Sham repetitive transcranial magnetic stimulation (sham rTMS)
- Record updated
- 15 July 2026
Who can take part
- Age
- 18 years to 35 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 22 criteriaShow less
Who can take part
- DSM-5 Diagnosis of Anorexia Nervosa
- Age 18-35 years
- Female
- Right-handed
- Body Mass Index (BMI) ≥ 16.0
- Voluntarily admitted to inpatient eating disorders unit at NYSPI
- Competent to provide informed consent
- English-speaking
- Medically stable
Who cannot take part
- Prior exposure to TMS
- Hearing loss (e.g., currently undergoing treatment with ototoxic medications or those with cochlear implants)
- Current substance use disorder or other co- morbid psychiatric condition requiring specialized treatment (e.g., psychosis)
- Diagnosis of major medical or neurological problem or taking medication that significantly increases risk for seizure or affects interpretation of findings (e.g., unstable hypertension, seizure disorder)
- Food restrictions (e.g., allergies) which impact greater than 30% of food choice task's choice options
- History of seizure
- Diagnosis of epilepsy, stroke, multiple sclerosis, traumatic brain injury, Alzheimer's and other neurodegenerative diseases, meningoencephalitis or intracerebral abscess, or parenchymal or leptomeningeal cancers
- High risk of suicide
- Indwelling ferromagnetic metallic object (e.g., pacemaker, pump), non- removable metal jewelry, medicinal patch or recent metallic ink tattoo
- Pregnancy
- Currently breast-feeding
- Significant claustrophobia
- Implanted devices or stimulators
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 35 years old?
Where in United States
- New York State Psychiatric InstituteNew York, United StatesContact: Alexandra F Muratore, PhDTaking people
About the trial
What the trial wants to find out
This study will examine the impact of high-frequency repetitive transcranial magnetic stimulation on food choice behavior and related neural activity.
The 2 groups in the trial
- High-frequency repetitive transcranial magnetic stimulation (HF-rTMS)Treatment being tested
Target: Region of right DLPFC with greatest resting-state functional connectivity to dorsal striatum (individualized functional target) Protocol: 10 pulses/sec, 4s trains, 120% MT, 3000 pulses/session
Treatment: High-frequency repetitive transcranial magnetic stimulation (active rTMS)
- Sham repetitive transcranial magnetic stimulation (sham rTMS)Sham treatment, for comparison
Target: Region of right DLPFC with greatest resting-state functional connectivity to dorsal striatum (individualized functional target) Protocol: same as HF-rTMS, with sham coil
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Deciphering the Neural Mechanisms of Restrictive Eating in Anorexia Nervosa Using Repetitive Transcranial Magnetic Stimulation
- Fit questions
- Built from NCT05918835, who can take part
- Record updated
- 15 July 2026