Sentinel Lymph Node Biopsy Compared With Lymph Node Removal in Early Ovarian Cancer

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for women with a suspicious adnexal mass that may be early-stage ovarian cancer. It tests sentinel lymph node biopsy against full lymph node removal.

Age

18 to 90 years

Sex

Women only

Disease stage

Suspicious adnexal mass for early-stage ovarian cancer. Advanced cancer (FIGO stage III and IV) found before or during surgery means a person cannot join.

Earlier treatment

No neoadjuvant ovarian cancer treatment. Recurrent ovarian cancer is not allowed.

Main reasons for not taking part

• Ovarian mass with low probability of early-stage ovarian cancer
• Medical or surgical reasons that rule out full surgical staging
• Metastatic cancer or a second primary cancer of the ovary
• Recurrent ovarian cancer
• Advanced ovarian cancer (FIGO stage III and IV) found before or during surgery

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 18 and 90 years old?YesNo

What the trial wants to find out

The primary goal of this prospective study is to define the efficacy of the sentinel lymph node biopsy (SLNB) procedure by comparing it to the results obtained from systematic lymphadenectomy, each performed in participants with a suspicious adnexal mass for early-stage ovarian cancer.

The group in the trial

• Sentinel Lymph Node Biopsy and Systematic Lymph Node Dissection (Single Arm)Treatment being tested

  This is a single arm interventional study in which the interventional and control arms are the same participant (each participant becomes its own control since the sentinel node biopsy- interventional arm - results are to be compared to systematic lymphadenectomy results-control arm). Intervention is injection of 2-4 mL sterile charcoal to the infundibulopelvic ligament or mesovarium of the suspicious adnexal mass followed by collection of stained sentinel lymph nodes and lymph nodes by systematic lymphadenectomy.

  Treatment: Sentinel lymph node biopsy (using sterile charcoal stain) in early ovarian cancer