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Taking people in GermanyNo phase

Studying why chronic inflammatory skin diseases differ between patients over time

Observes patients with several chronic inflammatory skin diseases to find factors shaping their course.

Plain-language title generated from the registry record
Registry title: Determinants of Chronic Inflammatory Skin Disease Trajectories

Key facts

Where
Kiel, GermanySee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 0 and 80 years old?

Source: NCT05928169, who can take part

Where in Germany

  • Department of Dermatology and Allergy, University Hospital Schleswig-HolsteinKiel, GermanyTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University Hospital Schleswig-Holstein
Trial code
NCT05928169
Record updated
28 August 2026
Original description
Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation, clinical features and course are also largely unknown. There are currently no reliable markers that could predict or delineate patient subgroups to support patient management. The aim of this project is to identify clinical and molecular factors that correlate with disease, disease subtypes and progression through in-depth long-term clinical characterization of patients with chronic inflammatory skin diseases and examination of individual biomaterials.Read full original descriptionShow less

Determinants of Chronic Inflammatory Skin Disease Trajectories

Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation, clinical features and course are also largely unknown. There are currently no reliable markers that could predict or delineate patient subgroups to support patient management. The aim of this project is to identify clinical and molecular factors that correlate with disease, disease subtypes and progression through in-depth long-term clinical characterization of patients with chronic inflammatory skin diseases and examination of individual biomaterials.

Inclusion: dermatologist-diagnosed inflammatory skin disease; informed consent.

Exclusion: concurrent participation in a clinical trial; use of systemic immunosuppressive therapy or phototherapy during the last 4 weeks or receipt of biologics therapy (e.g. dupilumab, tralokinumab) within the last 3 months; treatment of the target skin areas with topical corticosteroids, calcineurin inhibitors or emollients 24 hours before sample collection; subject and/or the legal guardians are not able to give written informed consent; pregnant and breastfeeding women.

ClinicalTrials.gov NCT05928169