Comparing two ways of removing the left chest artery for heart bypass
Tests two artery removal methods in people with coronary artery disease.
Plain-language title generated from the registry record
Registry title: Randomized Comparison of Skeletonized Versus Pedicled Left Internal Thoracic Artery
Key facts
- Where
- Graz, Innsbruck, and Vienna, AustriaSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT05931783, who can take part
Where in Austria
- Medical University of GrazGraz, AustriaNot yet recruiting
- Medical University of InnsbruckInnsbruck, AustriaTaking people
- Medical University of ViennaVienna, AustriaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Medical University Innsbruck
- Trial code
- NCT05931783
- Record updated
- 15 March 2024
- Original description
Internal thoracic arteries can be harvested in skeletonized or pedicled technique. Latest research has posed a potential adverse effect of skeletonizing the internal thoracic arteries on graft patency rates and clinical outcome. Prospective, randomized, multi-centre trials are necessary to investigate the impact of harvesting technique of left internal thoracic artery (LITA) on graft patency rates and clinical outcome after coronary artery bypass grafting.Read full original descriptionShow less
Randomized Comparison of HARVesting the Left Internal Thoracic Artery in a Skeletonized Versus Pedicled Technique: the HARVITA Trial
Internal thoracic arteries can be harvested in skeletonized or pedicled technique. Latest research has posed a potential adverse effect of skeletonizing the internal thoracic arteries on graft patency rates and clinical outcome. Prospective, randomized, multi-centre trials are necessary to investigate the impact of harvesting technique of left internal thoracic artery (LITA) on graft patency rates and clinical outcome after coronary artery bypass grafting.
The HARVITA trial compares skeletonized and pedicled harvesting technique of LITA regarding graft patency rates and patient survival.
Inclusion: Primary isolated CABG patients with multi-vessel disease (defined as ≥70 % stenosis of the left anterior descending artery (LAD) and ≥50% stenosis of circumflex and right coronary territory, with or without a ≥50% stenosis of the left main artery).
Exclusion: Preoperative mediastinal radiation therapy; Minimal invasive coronary artery bypass surgery; Any concomitant cardiac or non-cardiac procedures; Previous cardiac surgery; Known contrast agent allergy; Severe stenosis of the left subclavian artery/ left-sided subclavian steal syndrome; Iodine allergy; Intraoperative exclusion criteria:; Chronic kidney disease (GFR <60ml/min/1.73m²); Age > 80 years; Planned CABG without LITA use; Emergency operation; Life expectancy of less than 5 years; Pregnancy; Hyperthyroidism; Y/T graft off the LITA graft; LITA sequential grafting; LITA target vessel other than LAD.