NCT05938283Completed
Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous)
Source: ClinicalTrials.gov · Last updated 19 Feb 2026
Brief summary (registry, in English)
Pilot randomised trial to assess recruitment for a larger trial to compare the efficacy and adverse effects of the subcutaneous and transvenous ICD in patients with hypertrophic cardiomyopathy (HCM) and indication for ICD therapy, with no requirement for pacing
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 5 (actual)
- First submitted
- 13 Jun 2023
- Start date
- 10 Jan 2024
- Primary completion date
- 7 Jan 2026
- Lead sponsor
- Barts & The London NHS Trust
- Diseases
- Hypertrophic cardiomyopathy
- NCT number
- NCT05938283
What you commit to
- Study type: Interventional
- Participants enrolled: 5
- From 10 Jan 2024 to the primary completion date, 7 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have had a previous ICD implant
- Patients with a serious known concomitant disease with a life expectancy of less than one year
Other illness
- Patients having an indication for pacing therapy. E.g. sick sinus syndrome.
- Patient who receives cardiac contractility modulation therapy or are likely to receive cardiac contractility modulation therapy
Other
- Patients with sustained ventricular tachycardia less than 170 bpm
- Patients failing appropriate QRS/T-wave sensing with the automated S-ICD ECG automated patient screening provided by Boston Scientific
- A minimum of 1 sensing vector passing in supine, standing.
- Patients with incessant ventricular tachycardia
- Patients with circumstances that prevent follow-up (no permanent home or address, transient, etc.)
- Patients who are unable to give informed consent
- Patients who are not suitable for TV-ICD implantation, according to the discretion of the physician, are not screened for enrolment (SVC occlusion).
Who the study is looking for
- Hypertrophic Cardiomyopathy and a referred for ICD therapy with no pacing requirement.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Bartholomew's Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.