Using heart ultrasound scans and patient data to find causes of heart disease
Tests computer tools reading heart ultrasound scans to find heart disease causes.
Key facts
- Who runs it
- Hospices Civils de Lyon
- Where
- Pierre-Bénite, FranceSee the site
- Trial code
- Registry title
- Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data.
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- 1 Jan 2023
- Expected to end
- 1 Jan 2027
- Type of study
- Observational, 2 groups
- Treatments tested
- Determine the etiology of hypokinetic and hypertrophic heart disease on transthoracic echocardiography data alone
- Record updated
- 13 July 2023
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who have had a heart ultrasound (transthoracic echocardiography) with good image quality. It uses these images to build tools that find the cause of heart disease.
- Age
- 18 years or older
- Sex
- Women and men can join
Main reasons for not taking part
- Under 18 years old
- Patients under curatorship or guardianship
- Heart ultrasound with poor image quality
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- Patients with transthoracic echocardiography with satisfactory image quality (sufficient echogenicity)
Who cannot take part
- Minor patients
- Patients under curatorship or guardianship
Where in France
- Hopital Lyon SudPierre-Bénite, FranceContact: Pierre-Yves COURAND, MD, PhDTaking people
About the trial
What the trial wants to find out
Research hypothesis - Recent studies have shown that high-dimensional descriptors of the cardiac function can be efficiently exploited to characterize targeted pathologies. In this project, the investigators hypothesize that echocardiograms possess a wealth of information that is currently under-exploited and that, combined with relevant patient data, will allow the development of robust and accurate digital tools for etiological diagnosis.
Read full original descriptionShow less
Objectives - Based on key advances recently obtained in image analysis, notably by members of the consortium, the objective of this project is to develop rigorous and explainable cardiac disease prediction models from echocardiography based on the transformer paradigm (AI). The strength of this study lies in the development of a strong AI framework to model the complex interactions between high-quality image-based measurements extracted from echocardiograms and relevant patient data to automatically predict etiological diagnosis of cardiac diseases
The 2 groups in the trial
- Patients with hypokinetic cardiomyopathy.
The first arm includes patients with hypokinetic cardiomyopathy for whom echocardiographic data do not readily distinguish between a cause related to coronary artery disease or related to primary myocardial dysfunction, requiring invasive intervention, i.e., coronary angiography.
Treatment: Determine the etiology of hypokinetic and hypertrophic heart disease on transthoracic echocardiography data alone
- Patients with left ventricular hypertrophy related to hypertension/infiltrative myocardial disease
The second arm includes patients with left ventricular hypertrophy, whose aetiology may be various and whose workup is particularly extensive and expensive.
Treatment: Determine the etiology of hypokinetic and hypertrophic heart disease on transthoracic echocardiography data alone
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data.
- Plain-language title
- Using heart ultrasound scans and patient data to find causes of heart diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 13 July 2023