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Measuring insulin levels and insulin resistance in adults with PCOS and obesity

Observes fasting insulin and insulin resistance in adults with PCOS or obesity.

Key facts

Who runs it
Ali Chappell
Where
Houston, United StatesSee the site
Trial code
Registry title
Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
Status
Recruiting
People taking part
150 people, planned
Started
1 Feb 2024
Expected to end
Dec 2027
Type of study
Observational
Record updated
1 May 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 18 or older, with or without PCOS, who recently had fasting blood tests that include insulin.

Age
18 years or older
Sex
Men and women can both join.
Disease stage
People with and without a confirmed PCOS diagnosis, across a range of body mass index (BMI) values.
Biomarker or test result
Blood tests done within one month before joining after a fast of at least 8 hours: fasting insulin, hemoglobin A1c, a complete lipid panel and triglycerides. All results must be available.

Main reasons for not taking part

  • Under 18 years old
  • Another hormone disorder that affects insulin levels (for example insulin-secreting tumors)
  • Loss of more than 5% of body weight within the previous month
  • Pregnancy or breastfeeding
  • Acute illness or infection within the past 2 weeks

The registry criteria, word for word

Show all 5 criteriaShow less

Who can take part

  • Participants must have completed metabolic testing within one month prior to enrollment, including:
  • Fasting insulin
  • Hemoglobin A1c (A1c)
  • Complete lipid panel
  • Triglycerides Laboratory testing must be completed through a healthcare provider, an independent laboratory, or by using an Insara Insulin Testing Kit Laboratory values must be obtained following a minimum 8-hour fast Participants must have complete laboratory data for all required measures

Where in United States

  • Lilli HealthHouston, United StatesContact: Ali M Chappell, PhD, MS, RDTaking people

About the trial

What the trial wants to find out

The study aims to investigate the relationship between fasting insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) across various demographic factors, including age, sex, race/ethnicity, BMI, and polycystic ovary syndrome (PCOS) diagnosis. By analyzing these variables, the study seeks to identify potential variations in insulin levels, which could provide valuable insights into the impact of different factors on metabolic health and the development of insulin-related conditions.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Measuring Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
Plain-language title
Measuring insulin levels and insulin resistance in adults with PCOS and obesityGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
1 May 2026