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Studies how heart filling problems affect women having heart surgery

Observes women with left heart filling dysfunction undergoing cardiac surgery, comparing them with men.

Plain-language title generated from the registry record
Registry title: Effect of Left Ventricle Diastolic Dysfunction on Outcomes in Female Cardiac Surgery Patients

Key facts

Where
Amsterdam, NetherlandsSee the site

Where in Netherlands

  • Academic Medical CenterAmsterdam, NetherlandsTaking people

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Trial details

Who runs it
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Trial code
NCT05972356
Record updated
17 February 2026
Original description
The aim of this study is to evaluate the differences between males and females with LVDD, undergoing cardiac surgery. The investigators will look at perioperative factors such as body weight, body surface area, previous medical history, cardiac function measured by amongst others, transoesophageal echocardiography and haemodynamic parameters, transfusion, coagulation, cardiopulmonary bypass (CPB) related factors, inotropic requirements, risk, and outcome scores as well as complications, morbidity and mortality at 30 days. The investigators will evaluate these variables in an observational setting, with the goal of improving outcome in females after cardiac surgery in the future.Read full original descriptionShow less

The Effect of Left Ventricular DIastolic Dysfunction on Short Term Cardiac Surgery Outcomes in Female Cardiac patieNts

The aim of this study is to evaluate the differences between males and females with LVDD, undergoing cardiac surgery. The investigators will look at perioperative factors such as body weight, body surface area, previous medical history, cardiac function measured by amongst others, transoesophageal echocardiography and haemodynamic parameters, transfusion, coagulation, cardiopulmonary bypass (CPB) related factors, inotropic requirements, risk, and outcome scores as well as complications, morbidity and mortality at 30 days. The investigators will evaluate these variables in an observational setting, with the goal of improving outcome in females after cardiac surgery in the future.

Inclusion: All patients >18 years, who undergo cardiac surgery from 1 January 2023 till 31 December 2026 in the Amsterdam UMC.

Exclusion: Patients who object to the re-use of their care data.

ClinicalTrials.gov NCT05972356