NCT05972694Completed
Effect of Grapes in Inflammatory Bowel Disease
The Effect of Grapes in Inflammatory Bowel Disease
Source: ClinicalTrials.gov · Last updated 5 Mar 2026
Brief summary (registry, in English)
The overall objective of this pilot intervention study is to determine the impact of grape powder (46g/day freeze dried whole grape powder provided by the California Table Grape Commission) on the gut microbiotacomposition in adult patients with the IBD subtype Crohn's disease (CD).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 21 (actual)
- First submitted
- 24 Jul 2023
- Start date
- 16 Sept 2024
- Primary completion date
- 1 Aug 2025
- Lead sponsor
- Case Western Reserve University
- Diseases
- Crohn's disease
- NCT number
- NCT05972694
What you commit to
- Study type: Interventional
- Participants enrolled: 21
- From 16 Sept 2024 to the primary completion date, 1 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Known drug abuse.
- Change in IBD medication within past 4 weeks.
- No probiotic or antibiotic use for the previous 14 days
Other illness
- Short bowel syndrome.
- Individuals who lack consent capacity, including the mentally ill, prisoners, cognitively impaired participants, dementia patients.
- Known parasitic disease of the digestive system.
- Other conditions that would be a contraindication to consumption of the study diets or preclude the participant from completing the study.
- History of \<1 natural bowel movements per day.
- Known berry or grape allergy
Other
- Hospitalized patients.
- Symptomatic intestinal stricture.
- Presence of an ostomy.
- Well-founded doubt about the patients cooperation.
- Existing pregnancy or lactation.
- Unable to access to technology that permits the daily completion of study related activities.
- Body mass Index \<16 kg/m or ≥35.
- Documented C.difficile colitis within four weeks of screening.
Who the study is looking for
- Documented diagnosis of Crohns disease. CD outpatients in remission
- Harvey Bradshaw-index in remission (\<6 score)
- Capable of providing consent to participate.
- Able to complete daily surveys and take oral nutrition
- Able to record daily meal intake
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospitals Cleveland Medical Center* Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
Related publications
- Effect of Short-Term Grape Powder Supplementation in Patients with Crohn's Disease: A Pilot Study.Nutrients · 2026 · PMID 42356234
This page is information, not medical advice. Discuss any trial with your doctor.