Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
Key facts
- Who runs it
- Karolinska Institutet
- Where
- Stockholm, SwedenSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 90 people, planned
- Started
- 25 Sept 2023
- Expected to end
- 15 Jul 2029
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- PIP joint denervation
- Patient education plus exercise
- Record updated
- 2 December 2024
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- Age ≥ 18 years
- Chronic symptomatic osteoarthritis in the PIP-joint
- Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren \& Lawrence, 1957)
- Clinical signs of PIP-joint arthritis
Who cannot take part
- Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment
- Ongoing infection in the hand
- Inflammatory arthritis
- Inability to co-operate with the follow-up protocol
Where in Sweden
- Department of Hand Surgery SödersjukhusetStockholm, SwedenContact: Elin Swärd, MD, PhDTaking people
About the trial
What the trial wants to find out
The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are:
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* Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise).
Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.
The 2 groups in the trial
- Surgical treatmentExisting treatment, for comparison
PIP joint denervation is performed through a volar approach.
Treatment: PIP joint denervation
- Non-surgical treatmentExisting treatment, for comparison
An education and exercise program.
Treatment: Patient education plus exercise
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS), a Randomized Controlled Trial
- Record updated
- 2 December 2024