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Tests spinal cord electrical stimulation to help arm movement after stroke

Tests spinal cord electrical stimulation to activate arm muscles in adults with stroke paralysis.

Plain-language title generated from the registry record
Registry title: Epidural Electrical Stimulation for Stroke Patients - Improve Motor and Sensory Function and Alleviate Pain

Key facts

Where
Hualien City, TaiwanSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 20 to 70 who had a first-ever stroke with weakness on one side of the body. They are expected to have spinal cord stimulation surgery.

Age
20 to 70 years
Sex
All sexes can join.
Disease stage
First-ever stroke with clear symptoms and weakness on the right or left side. Fugl-Meyer scale score higher than 7 and lower than 45.
Earlier treatment
Must not take anticoagulant, anti-spasticity or anti-epileptic medicines before or during the study. Spinal cord stimulation surgery is expected.

Main reasons for not taking part

  • Pregnancy or breastfeeding
  • Major depressive disorder, or mental illness within one year or treated in the past
  • Significant memory or thinking problems (MMSE below 24)
  • Heart, blood vessel, muscle or bone disease or injury that stops full part in physical therapy
  • Joint contractures too severe to take part

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 20 and 70 years old?

Source: NCT05981989, who can take part

Where in Taiwan

  • Buddhist Tzu Chi Medical Foundation Hualien Tzu Chi HospitalHualien City, TaiwanContact: Sheng-Tzung Tsai, M.D., Ph.D.Taking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Buddhist Tzu Chi General Hospital
Trial code
NCT05981989
Record updated
19 September 2025
Original description
This study aims to verify whether epidural electrical stimulation (EES) of the cervical spinal cord can activate muscles of the upper limbs in people with hemiplegia following a stroke.Read full original descriptionShow less

Epidural Electrical Stimulation for Stroke Patients - Improve Motor and Sensory Function and Alleviate Pain

This study aims to verify whether epidural electrical stimulation (EES) of the cervical spinal cord can activate muscles of the upper limbs in people with hemiplegia following a stroke.

Inclusion: Between 20 and 70 years of age; First-ever clinical manifest stroke; Right or left hemiparesis; Scores higher than 7 and lower than 45 on the Fugl-Meyer scale; Expected will undergo spinal cord stimulation surgery; Able to comply with procedures and follow up; Stable medical condition without cardiopulmonary disease or dysautonomia that would contraindicate participation in upper extremity rehabilitation or testing activities.

Exclusion: Receiving anticoagulant, anti-spasticity or anti-epileptic medications prior to or throughout the duration of the study; Have Major depressive disorder; Had a mental illness within one year or been treated in the past; Have significant cognitive impairment (MMSE<24) or serious disease that could affect the ability to participate in study activities; Cardiovascular or musculoskeletal disease or injury that would prevent full participation in physical therapy intervention; Pregnancy or breast feeding; Unable to read and/or comprehend the consent form; Have concerns about this trial and do not sign consent; Presence of joint contractures deemed by study clinician/investigator to be too severe to participate in study activities.

ClinicalTrials.gov NCT05981989