Magnetic Resonance Elastography Scans to Study Glioma Tumor Stiffness
Tests a special MRI scan that measures how stiff brain tumors called gliomas are.
Plain-language title generated from the registry record
Registry title: Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
Key facts
- Where
- Shenyang, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a glioma (a brain tumour) who will have surgery and a special MRI scan (MRE) of the tumour before it.
- Age
- Older than 18 years, up to 80 Years
- Sex
- All sexes can join.
- Disease stage
- Glioma with a tumor diameter > 2 cm (0.8 in).
- Earlier treatment
- People cannot have had earlier treatment for glioma.
- Biomarker or test result
- IDH test results must be available.
Main reasons for not taking part
- Previous treatment for glioma
- Cannot complete the MRE scan, for example because of vibration discomfort or claustrophobia
- MRE images of poor quality, for example from motion
- Surgery not going ahead after the MRE
- Missing IDH results
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT05990244, who can take part
Where in China
- Shengjing HospitalShenyang, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shengjing Hospital
- Trial code
- NCT05990244
- Record updated
- 2 December 2025
- Original description
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.Read full original descriptionShow less
Comprehensive Assessment of Tumor Stiffness and Adhesion in Glioma Using Magnetic Resonance Elastography: A Prospective Study
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.
Inclusion: age older than 18 years; Karnofsky performance status higher than 60; with written informed consent; MRE performed within one week before surgery; tumor diameter > 2 cm.
Exclusion: previous treatment for glioma; failure to proceed with surgery after MRE; inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia); completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude); missing IDH results.