Under construction – not a live service
Sign in
Taking people in United StatesNo phase

Training program before epilepsy surgery for adults with epilepsy

Tests a training program before epilepsy surgery in adults with epilepsy.

Plain-language title generated from the registry record
Registry title: Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

Key facts

Where
Cleveland, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 60 years old?

Source: NCT05992402, who can take part

Where in United States

  • Cleveland ClinicCleveland, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Kayela Arrotta
Trial code
NCT05992402
Record updated
18 June 2026
Original description
The goal of this clinical trial is to learn if new educational program prior to epilepsy surgery can either decrease the risk of cognitive decline after surgery or be a help to those patients who experience a decline after undergoing epilepsy surgery.Read full original descriptionShow less

Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

The goal of this clinical trial is to learn if new educational program prior to epilepsy surgery can either decrease the risk of cognitive decline after surgery or be a help to those patients who experience a decline after undergoing epilepsy surgery.

Participants will participate in 2 individual virtual sessions and 4 virtual group sessions over the course of 5-6 weeks prior to their epilepsy surgery. They will asked to fill out online surveys and questionnaires at various times throughout the study, up to 12 months after their surgery.

To see if the educational program works, researchers will compare those participating in the educational program with those that are receiving the standard epilepsy care prior to surgery.

Inclusion: Adults, aged 18-60 years old, with diagnosed epilepsy who have been confirmed as an appropriate surgical candidate by their epileptologist; Able to independently provide informed consent; Fluent in English; Reading abilities at or above 8th grade level as determined by the Wide Range Achievement Test- 4th Edition (WRAT-4), Reading subtest; Internet access and the ability to participate in online video streaming; No history of resective or ablative neurosurgery, but this does not include neuromodulation therapies for epilepsy (e.g., RNS, VNS, DBS); Willing and able to participate in cognitive intervention.

Exclusion: Ongoing litigation related to the cause of epilepsy, unless litigation is related to short term or long-term disability application; Undergoing intensive medical treatment for serious or life-threatening illness (e.g., chemotherapy, etc.) that would impact study participation; Serious psychiatric condition that could interfere with participation, such as schizophrenia, active psychosis, active mania, and current suicidal ideation; Any patient that has engaged in any form of cognitive rehabilitation/intervention within the last 6 months; Significant hearing and/or vision loss that would preclude them from participating in remote cognitive testing and engaging in the cognitive intervention.

ClinicalTrials.gov NCT05992402