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Mirror therapy and augmented reality training for stroke recovery

Tests mirror therapy followed by augmented reality training in adults recovering from stroke.

Plain-language title generated from the registry record
Registry title: Mirror Therapy and Augmented Reality in Stroke Rehabilitation

Key facts

Where
New Taipei City, Taichung, and Taipei, TaiwanSee the 5 sites

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults 3 months to 3 years after a first-ever stroke on one side of the brain, who can walk and follow instructions. It tests mirror therapy and augmented reality.

Age
30 to 80 years
Sex
All sexes can join.
Disease stage
First-ever stroke on one side, at least 3 months and at most 3 years ago. Arm function score (FMA-UE) above 10. No severe stiffness (spasticity) in the affected arm (modified Ashworth scale below 3).

Main reasons for not taking part

  • Acute inflammation
  • Serious medical problems or poor physical condition that could harm participation
  • Severe vision problems or other major neurologic diseases
  • Taking part in other studies during this study
  • Cannot stand in a step-standing position for at least 30 seconds or walk at least 10 meters (with or without a device)

Read by machine on 9 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 30 and 80 years old?

Source: NCT05993091, who can take part

Where in Taiwan

  • Taipei Hospital, Ministry of Health and WelfareNew Taipei City, TaiwanContact: Keh-chung Lin, ScDTaking people
  • Taipei Tzu Chi Hospital, Buddhist Tzu Chi FoundationNew Taipei City, TaiwanContact: Keh-chung Lin, ScDTaking people
  • Fongyuan Hospital, Ministry of Health and WelfareTaichung, TaiwanContact: Keh-chung Lin, ScDTaking people
  • National Taiwan University HospitalTaipei, TaiwanContact: Keh-chung Lin, ScDTaking people
  • Wan Fang Hospital, Taipei Medical UniversityTaipei, TaiwanContact: Keh-chung Lin, ScDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
National Taiwan University Hospital
Trial code
NCT05993091
Record updated
5 February 2026
Original description
This research is in line with the National Health Research Institutes (NHRI) Innovative Research Grant priority to address innovative treatment strategies for neurological disorders that are in desperate need of scientific scrutiny. Stroke is one of the major medical conditions that leads to long-term disability and causes a heavy health care and financial burden. To meet multidimensional needs of patients with stroke, hybrid interventions that combine different approaches are needed due to the complexity of stroke. Our previous research funded by the NHRI has been published and translated to stroke rehabilitation, particularly in the priming and synergic effects of robotic-assisted training and/or mirror therapy (MT). To extend from our previous research, the investigators will combine MT with augmented reality (AR), an emerging adjunct therapy in stroke rehabilitation. An AR-based intervention provides an intensive, repetitive, and context-rich training program, leading to an interesting environment with real-time feedback to increase motivation and participation.Read full original descriptionShow less

Outcomes of Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation

This research is in line with the National Health Research Institutes (NHRI) Innovative Research Grant priority to address innovative treatment strategies for neurological disorders that are in desperate need of scientific scrutiny. Stroke is one of the major medical conditions that leads to long-term disability and causes a heavy health care and financial burden. To meet multidimensional needs of patients with stroke, hybrid interventions that combine different approaches are needed due to the complexity of stroke. Our previous research funded by the NHRI has been published and translated to stroke rehabilitation, particularly in the priming and synergic effects of robotic-assisted training and/or mirror therapy (MT). To extend from our previous research, the investigators will combine MT with augmented reality (AR), an emerging adjunct therapy in stroke rehabilitation. An AR-based intervention provides an intensive, repetitive, and context-rich training program, leading to an interesting environment with real-time feedback to increase motivation and participation.

Inclusion: a first-ever unilateral stroke ≥3 months and ≤3 years; age between 30 and 80 years (Kwakkel et al., 1999); baseline Fugl-Meyer Assessment Upper Extremity (FMA-UE) score >10 (Fugl-Meyer et al., 1975); no severe spasticity in any joints of the affected arm (modified Ashworth scale <3) (Charalambous, 2014); ability to follow the instructions of the evaluator and therapists; the ability to maintain a step-standing position for at least 30 seconds (Lloréns et al., 2015); ability to walk a minimum of 10 meters, with or without a device (Park et al., 2017); no severe vision impairments or other major neurologic diseases; no participation in other studies during the study period; willingness to provide informed written consent.

Exclusion: serious medical problems or poor physical conditions that might be detrimental to study participation; acute inflammation.

ClinicalTrials.gov NCT05993091