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Taking people in United StatesNo phase

Parathyroid Tumor Clonal Status

Key facts

Who runs it
Washington University School of Medicine
Where
St Louis, United StatesSee the site
Trial code
Status
Recruiting
People taking part
839 people, planned
Started
28 Jul 2023
Expected to end
31 Jan 2032
Type of study
Observational
Record updated
12 May 2026

Who can take part

Age
18 years to 80 years
Sex
Women only
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 7 criteriaShow less

Who can take part

  • 1. Diagnosed with hyperparathyroidism (primary, secondary, or tertiary), biochemically confirmed (e.g., serum calcium and/or intact PTH consistent with the underlying etiology), and undergoing clinically indicated management
  • Female and male patients
  • Age ≥ 18 years
  • Ability to understand and willingness to sign an IRB approved written informed consent document (or that of legally authorized representative, if applicable)

Who cannot take part

  • Patients currently taking lithium or with a history of lithium use
  • Patients with a history of cervicofacial irradiation
  • Pregnant patients

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Where in United States

  • Washington University School of MedicineSt Louis, United StatesContact: Bryan BearTaking people

About the trial

What the trial wants to find out

To define the frequency of monoclonal-X and polyclonal-X tumors in hyperparathyroid disorders patients having PTX and to define the relationship between parathyroid tumor clonal status and multiple gland neoplasia (MGN), we will compare surgical and pathologic outcomes to tumor clonal status in a multicenter cohort of patients having bilateral neck exploration (BNE) and PTX (primary objectives).

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
A Phase 2 Biomarker Study of Parathyroid Tumor Clonal Status in Hyperparathyroid Disorders (Primary, Secondary, and Tertiary)
Fit questions
Built from NCT05997810, who can take part
Record updated
12 May 2026