Checking a New Microscope for Quick Lung Cancer Diagnosis
Checks a new microscope that images lung tissue samples in adults suspected of lung cancer.
Plain-language title generated from the registry record
Registry title: Validation of Rapid On-site Diagnostics in Early Stage Lung Cancer Sampling With a Higher Harmonic Generation Microscope
Key facts
- Where
- Nijmegen, NetherlandsSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a lung lesion who need a test or treatment for it. Biopsies are imaged with a new microscope during the procedure.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- A lung lesion that needs a diagnostic or treatment evaluation under current clinical guidelines or by team decision.
Main reasons for not taking part
- Bleeding disorders
- Younger than 18 years
- Unable to give consent
- Not fit for navigation bronchoscopy or for surgical removal
Read by machine on 12 November 2026.
Where in Netherlands
- RadboudumcNijmegen, NetherlandsContact: Roel LJ Verhoeven, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Radboud University Medical Center
- Trial code
- NCT06007261
- Record updated
- 24 January 2024
- Original description
The aim of this study is to verify a new microscopic technique in diagnosing patients suspected of lung cancer. Patients will undergo navigational bronchoscopy or surgical resection as a part of standard of care. Biopsies taken during this procedure will be imaged for a few minutes with a higher harmonic generation (HHG) microscope, after which the material is taken to the pathology department for histopathology assessment, which is currently the golden standard for diagnosis.Read full original descriptionShow less
Validation and Added Clinical Value of Rapid On-site Diagnostics in Early Stage Lung Cancer Sampling With a Higher Harmonic Generation Microscope
The aim of this study is to verify a new microscopic technique in diagnosing patients suspected of lung cancer. Patients will undergo navigational bronchoscopy or surgical resection as a part of standard of care. Biopsies taken during this procedure will be imaged for a few minutes with a higher harmonic generation (HHG) microscope, after which the material is taken to the pathology department for histopathology assessment, which is currently the golden standard for diagnosis.
Inclusion: ASA physical status 1-3; Age 18 years or older; A pulmonary lesion with an indication for diagnostic or therapeutic evaluation following current clinical guidelines and/or as decided by multi-disciplinary team consultation.
Exclusion: Unfit for navigation bronchoscopy and/or unfit for surgical resection as per guideline recommended care and multi-disciplinary tumor board decision making; Bleeding disorders; Less than 18 years old; Inability to consent.