Tests brain stimulation to ease suicidal thoughts in depression
Tests brain stimulation with a mild current in adults with treatment-resistant depression.
Plain-language title generated from the registry record
Registry title: Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation
Key facts
- Where
- Faye-l'Abbesse and Poitiers, FranceSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with depression and suicidal thoughts who are taking a stable antidepressant. It tests brain stimulation with a weak electric current (tDCS).
- Age
- Over 18 years
- Sex
- All sexes can join.
- Disease stage
- A recurrent or single depressive episode (DSM IV criteria), with a MADRS score of 20 or more and an SSI score above 3.
- Earlier treatment
- Stable antidepressant treatment for 3 weeks.
Main reasons for not taking part
- Depression with psychotic features, schizophrenia, or alcohol or other substance dependence or abuse
- High suicide risk (MADRS item 10 above 4) without hospitalization
- Already had electroconvulsive therapy for this episode and did not respond
- Contraindication to tDCS, such as a metal implant in the brain or a pacemaker
- Pregnant or breastfeeding women
Read by machine on 12 November 2026.
Where in France
- Centre Hospitalier Nord-Deux-SèvresFaye-l'Abbesse, FranceContact: Issa WassoufTaking people
- Centre Hospitalier Henri LaboritPoitiers, FranceContact: Ghina Harika-GermaneauTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Centre Hospitalier Henri Laborit
- Trial code
- NCT06009523
- Record updated
- 23 October 2026
- Original description
The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideationRead full original descriptionShow less
Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation in Treatment-resistant Depression : a Pilot Study
The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideation
Inclusion: Age over 18 years; Written informed consent; Diagnosis of recurrent or isolated depressive episode according to DSM IV criteria (A.P.A. 1994); Stable antidepressant treatment for 3 weeks; MADRS score ≥ 20; SSI score > 3; Subject affiliated to a health insurance system; Woman with effective contraception and agreeing to maintain it throughout the study period.
Exclusion: Patient who has already undergone an electroconvulsive therapy course for the current episode and does not respond to this treatment; Contraindication to tDCS: intracerebral metallic implant (with the exception of dental implants), cardiac pacemaker, active or non-implanted devices in the region of the head, acute eczema in the planned stimulation area; Depression with psychotic features Axis I (DSM IV) co-morbid diagnosis of schizophrenia, alcohol and/or other substance dependence (or abuse) (lifetime); Patient deprived of liberty; Patient with high suicide risk (item 10 MADRS > 4) in the absence of hospitalization; Pregnant, parturient or breastfeeding woman; Simultaneous participation in another interventional research.