Studying gene markers of scarring in endometriosis and disease severity
Compares gene activity in endometriosis tissue types and healthy-lining tissue in women.
Plain-language title generated from the registry record
Registry title: Molecular Markes of Fibrosis of Endometriosis and Their Use in Predicting Disease Severity
Key facts
- Where
- Prague, CzechiaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT06020482, who can take part
Where in Czechia
- General University Hospital in PraguePrague, CzechiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- General University Hospital, Prague
- Trial code
- NCT06020482
- Record updated
- 31 August 2023
- Original description
The primary aim of the project is to analyse gene expression in individual types of ectopic endometrium (ovarian endometriosis, peritoneal endometriosis, deep infiltrating endometriosis) and compare it with gene expression in eutopic endometrium. The analysis focuses on the identification of genes with significantly increased expression in each type of ectopic endometrium and comparison of their expression with the degree of disease, ovarian reserve and clinical manifestations of the disease (pain, infertility).Read full original descriptionShow less
Molecular Markes of Fibrosis of Single Types of Endometriosis and Their Use in Predicting Disease Severity
The primary aim of the project is to analyse gene expression in individual types of ectopic endometrium (ovarian endometriosis, peritoneal endometriosis, deep infiltrating endometriosis) and compare it with gene expression in eutopic endometrium. The analysis focuses on the identification of genes with significantly increased expression in each type of ectopic endometrium and comparison of their expression with the degree of disease, ovarian reserve and clinical manifestations of the disease (pain, infertility).
Inclusion: women (18-45 years); signed informed consent with the study; absence of hormonal treatment 3 months before the planned procedure; laparoscopically and histologically confirmed endometriosis dg; patients without endometriosis; patients who are undergoing an elective laparoscopic or hysteroscopic procedure in our department for another benign indication; patients with excluded malignant disease.
Exclusion: patients who do not meet the inclusion criteria during surgery; patient younger than 18 years of age or older than 45 years of age; absence of informed consent.