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Compares two heart pacing methods for atrial fibrillation risk in heart block

Compares two pacing sites for heart rhythm in adults with atrioventricular block.

Plain-language title generated from the registry record
Registry title: The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block

Key facts

Where
Beijing, ChinaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 85 years old?

Source: NCT06023784, who can take part

Where in China

  • Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College HospitalBeijing, ChinaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Peking Union Medical College Hospital
Trial code
NCT06023784
Record updated
21 September 2026
Original description
This is a single-center, randomized controlled study. The aim of this study is to compare the impact of left bundle branch area pacing versus traditional right ventricular pacing on the incidence of atrial fibrillation in patients with atrioventricular block.Read full original descriptionShow less

The Impact of Left Bundle Branch Area Pacing Versus Right Ventricular Pacing on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block: a Randomized Controlled Trial

This is a single-center, randomized controlled study. The aim of this study is to compare the impact of left bundle branch area pacing versus traditional right ventricular pacing on the incidence of atrial fibrillation in patients with atrioventricular block.

Inclusion: Adult patients aged 18-85; AV block patients with ventricular pacing indications and the expected rate of ventricular pacing(VP)> 40%, including (a) third-degree AV block; (b) second degree AV block (type II); (c) intermittent advanced AV block with expected VP>40%; (d) symptomatic first degree AV block and PR interval on ECG > 300ms; Signed informed consent.

Exclusion: Patients with the history of atrial fibrillation; Having difficulties in follow-up: Those who cannot accept 2-year follow-up on time due to physical condition or other reasons; Surgery is required within 1 year due to severe structural heart disease; Patients with tricuspid mechanical valve replacement, or congenital heart disease (including transposition of the great arteries, or permanent left superior vena cava, etc); Baseline echocardiographic assessment of patients with impaired LV function (LVEF<50%); Pacemaker replacement without new implanted ventricular electrodes; AV block resulting from: (a) Hypertrophic cardiomyopathy(HCM), (b) ventricular septal defect repair, and those who are unlikely to achieve successful LBBAP procedure.

ClinicalTrials.gov NCT06023784