Compares two sutures for closing the vagina after keyhole hysterectomy
Compares two suture types for closing the top of the vagina in women.
Plain-language title generated from the registry record
Registry title: Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
Key facts
- Where
- Frankfurt am Main, GermanySee the site
Where in Germany
- Klinikum Sachsenhausen der DGDFrankfurt am Main, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Aesculap AG
- Trial code
- NCT06024109
- Record updated
- 2 June 2026
- Original description
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic surgeries without an increase in the complication rate.Read full original descriptionShow less
Prospective, International, Randomized, Multicentric, Controlled Study on the Performance of SYMMCORA® Mid-term Unidirectional Barbed Suture Versus V-loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic surgeries without an increase in the complication rate.
Secondly, the superiority of SYMMCORA®, mid-term unidirectional compared to the V-Loc®, unidirectional will be assessed regarding the mean time to close the vaginal cuff. The study will be performed in routine clinical setting, the only difference will be the randomization into two different suture groups. Both suture materials which will be applied to approximate the vaginal cuff are approved and carrying the CE-marks. Additionally, both sutures will be applied in their intended use. Neither additional invasive measures nor additional burden in regard to the patient will be performed.
Inclusion: Females undergoing an elective, laparoscopic total hysterectomy; Age ≥ 18 years; Written informed consent.
Exclusion: Emergency surgery; Open surgery; Patients undergone immunosuppressive drug treatment within the prior 6 months; Patients with hypersensitivity or allergy to the suture material; Participation in another clinical study; Non-compliance of patient.