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SuspendedNo phase

Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks

Key facts

Who runs it
Medical University of South Carolina
Where
Charleston, United StatesSee the site
Trial code
Status
Suspended
People taking part
538 people, planned
Started
Nov 2026
Expected to end
31 Dec 2027
Type of study
Interventional, 2 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • Decreased Neuro Checks overnight
Record updated
9 April 2026
Why it stopped
Awaiting grant funding

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 2 criteriaShow less

Who can take part

  • Admitted with acute stroke Age greater or equal to 18 years old Medical and neurologic stability for discontinuation of neuro-checks, determined by the Stroke Service NP and Attending Physician (no uncontrolled fluctuation in vital signs, seizure like activity or worsening neurologic function) Ability to give informed consent, or identifiable surrogate decision maker

Who cannot take part

  • Surgical hemorrhagic stroke Subarachnoid hemorrhage Medical or neurologic instability Pregnancy Inmates

Where in United States

  • Medical University of South CarolinaCharleston, United States

About the trial

What the trial wants to find out

There have been limited studies on delirium in patients hospitalized with acute stroke. There have been no studies on the potential impact of overnight neuro-checks and resulting sleep disruption on delirium or other outcomes. Additional research is needed to determine if overnight checks are necessary or even harmful. We aim to find out if stopping overnight neuro checks may prevent delirium and benefit the patient.

The 2 groups in the trial

  • Standard of Care Neuro ChecksNo study treatment, for comparison

    If a patient is randomized to the control group, they will continue to have neuro-checks conducted every 2-4 hours as ordered by the primary team, as per standard of care on the acute stroke service.

  • Absence of Neuro ChecksTreatment being tested

    If a patient is randomized to the intervention group, the team will discontinue neuro-checks between 8pm and 4am. They will otherwise receive the same care, including overnight vital signs. If the patient has a neurologic or hemodynamic change, the primary team may elect to restart the overnight neuro-checks.

    Treatment: Decreased Neuro Checks overnight

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
9 April 2026