Single Exercise Session Effect on Brain Insulin Response in Adults
Compares one moderate and one intense exercise session in adults with obesity or insulin resistance.
Plain-language title generated from the registry record
Registry title: Exercise Training on Brain Insulin Responsiveness
Key facts
- Where
- Tübingen, GermanySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 65 years old?
Source: NCT06039787, who can take part
Where in Germany
- University Clinic Tübingen, Department of Internal Medicine IVTübingen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital Tuebingen
- Trial code
- NCT06039787
- Record updated
- 8 November 2023
- Original description
The overarching goal of the current study is to investigate the effect of one acute bout of exercise on the brain insulin responsiveness in a cross-over study design. To this end, investigators will compare the effect of two single endurance exercise sessions with different intensities, namely moderate intensity continuous training (MICT) and high-intensity-interval-training (HIIT), which will be performed in a randomized order. This will be compared to a waiting control condition.Read full original descriptionShow less
Effects of One Exercise Training Session on Brain Insulin Responsiveness
The overarching goal of the current study is to investigate the effect of one acute bout of exercise on the brain insulin responsiveness in a cross-over study design. To this end, investigators will compare the effect of two single endurance exercise sessions with different intensities, namely moderate intensity continuous training (MICT) and high-intensity-interval-training (HIIT), which will be performed in a randomized order. This will be compared to a waiting control condition.
Inclusion: BMI between ≥ 19.5 to 39 kg/m2-; Less than 150 min/week for moderate-intensity physical activity; Less than 75 min/week for Vigorous- intensity exercise (WHO recommendations for regular physical activity of adults); Written consent to participate in the study; Written consent to be informed about incidental findings.
Exclusion: Taking psychotropic drugs; Regular use of analgesic drugs; Previous bariatric surgery; Type 2 diabetes, cardiovascular diseases such as chronic heart failure, myocardial infarction, status post stroke; Limitations to participate in ergometer-based exercise (balance and coordination disorders, orthopedic problems, …); History of severe mental or somatic disorders including neurological diseases (incl. epileptic seizures and migraines); Acute infection within the last 4 weeks; Other diseases that in the opinion of the investigator may jeopardize the success of the study or indicate a risk to the volunteer; Metal implants which cannot be removed as pacemakers, artificial heart valve, electrical devices as insulin pumps, large tattoos, retainer over more than 4 teeth, contraceptive coil, implanted magnetic metal parts as screws or plates after a surgery; Taking medications that influence glucose metabolism; Hemoglobin values less than 12g/dl for women, less than 14 g/dl for men; Insufficient knowledge of the German language; Persons who cannot legally give consent; Pregnancy or lactation; Taking anticoagulant agents; Current participation in a lifestyle intervention study or a pharmaceutical study; Persons with claustrophobia; Temperature-sensitive person; Persons with tinnitus or increased sensitivity to loud sounds.