Tests trauma therapy for people with PTSD and psychosis
Tests trauma-focused prolonged exposure therapy in adults with PTSD and psychosis.
Plain-language title generated from the registry record
Registry title: Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder
Key facts
- Where
- Hamburg, GermanySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a psychotic disorder who also have post-traumatic stress disorder (PTSD). They must be willing to be randomised and to take part in trauma-focused therapy.
- Age
- At least 18 years old.
- Sex
- All sexes can join.
- Disease stage
- A psychotic disorder (F20) or an affective disorder with psychotic symptoms (F30) according to DSM-5, plus PTSD according to DSM-5 with a CAPS-5 score of 23 or more.
- Earlier treatment
- No change in neuroleptic or antidepressant therapy within the last 4 weeks.
Main reasons for not taking part
- Change in neuroleptic or antidepressant therapy in the last 4 weeks
- Any substance dependence with continued use, other than nicotine or caffeine
- IQ of 70 or less
- Acute suicidality
- Pregnant women
Read by machine on 12 November 2026.
Where in Germany
- Medicalschool HamburgHamburg, GermanyContact: Susanne Sarkar, Dr.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Medicalschool Hamburg
- Trial code
- NCT06048172
- Record updated
- 21 September 2023
- Original description
Psychosis patients with comorbid PTSD will be treated with trauma therapy.Read full original descriptionShow less
How Effective and Safe is Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder? Treatment Trauma and Psychosis -TEP
Psychosis patients with comorbid PTSD will be treated with trauma therapy.
Inclusion: Presence of a psychotic disorder (F20) or affective disorder with psychotic symptoms(F30) according to DSM-5; comorbid post-traumatic stress disorder (PTSD) according to DSM-5 (CAPS-5 score ≥ 23); At least 18 years old; Good knowledge of the German language; Willingness to participate in randomisation and trauma-focused therapy.
Exclusion: Changes in neuroleptic or antidepressant therapy within the last 4 weeks (exclusion of drug effects); Any substance dependence with continued use other than nicotine and/or caffeine dependence; IQ of 70 or less; Acute suicidality; Pregnant women.