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Objective Characterizatoion of Repetitive Behaviors

Key facts

Who runs it
Institut National de la Santé Et de la Recherche Médicale, France
Where
France3 sites in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
50 people, planned
Started
28 Dec 2023
Expected to end
27 Dec 2027
Type of study
Interventional, 2 groups
Treatments tested
  • EEG
  • MRI
Record updated
12 February 2026

Who can take part

Age
15 years to 65 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • To be more of 15 years old or less than 65 years old
  • To suffer from OCD and/or GTS (depressive, anxious and attention deficit hyperactivity disorder (ADHD) comorbidities are accepted)
  • To be registered to the french social security (or something equivalent)
  • To give written consent to participate to the research
  • To have contraception for women participants (or to not have any sexual activity)

Who cannot take part

  • Patients with any other psychiatric disorders than those mentioned in the inclusion criteria
  • Patients with any other neurological disorder than GTS
  • Patients who are not able to take decisions for themselves
  • Pregnant women
  • Patients not allowed to get MRI due to contraindication
  • Patients not speaking french

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 15 and 65 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

Introduction:

Read full original descriptionShow less

Repetitive behaviors (RB) constitute a broad range of symptoms across different psychiatric/neurologic disorders. The most famous are stereotypies (found in autism), compulsions (found in obsessive-compulsive-disorder, OCD) and tics (found in Gilles de la Tourette syndrome, GTS). For some patients, it is sometime difficult to distinguish the nature of the repetitive behaviors presented, however this distinction is crucial in order to chose the appropriate treatment.

Aim:

In our study, the investigators will try to define electrophysiological and accelerometric marker of both OCD and tics to allow objective distinction between both tics and compulsions.

Method:

Subjects: Both OCD and GTS patients will be recruited, 25 patients in each group.

Protocol: our study protocol will involve two step: a step in laboratory, another step at patient home.

* first step: both patients group will be recorded through a high density EEG and a portative EEG while doing a task of symptom provocation. Then they will get an anatomical MRI for source recontruction. Finally, the patients will have to mimic their symptom while wearing an accelerometer (a smartwatch). * second step: both patient groups will be recorded at home through a portative EEG while tagging their symptom through a smartwatch (also used for accelerometry). After the recording, the patients will keep the smartwatch for 2 weeks, still tagging their sympoms (compulsions or tics).

The 2 groups in the trial

  • GTS groupTreatment being tested

    This arm will be studied to get some electrophysiological marker of tics. The patients will be their own control (periods with symptoms vs. free symptoms periods).

    Treatment: EEG and MRI

  • OCD groupTreatment being tested

    This arm will be studied to get some electrophysiological marker of compulsions. The patients will be their own control (periods with symptoms vs. free symptoms periods).

    Treatment: EEG and MRI

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Actimetric and Electrophysiological Analyses of Repetitive Behaviors (Tics and Compulsions)
Fit questions
Built from NCT06050369, who can take part
Record updated
12 February 2026