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Advanced MRI to map brain networks in drug-resistant epilepsy

Tests advanced MRI scans to find seizure networks in people with drug-resistant epilepsy.

Plain-language title generated from the registry record
Registry title: Epileptogenic Network Visualisation With Advanced MRI

Key facts

Where
Brussels, BelgiumSee the site

Where in Belgium

  • Cliniques Universitaires St-LucBrussels, BelgiumTaking people

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Trial details

Who runs it
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Trial code
NCT06059157
Record updated
15 June 2026
Original description
The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient.Read full original descriptionShow less

Epileptogenic Network Visualisation With Advanced MRI

The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient.

The investigators aim to compare epileptogenic network identification with stereo-EEG (used as glod standard) with the identification of the same network using advanced MRI (rs-fMRI, microstructural analysis of white matter, ...). The main goals are to:

1. Compare the accuracy of network identification. 2. Analyse the effect of the MRI sequences on candidates selection and target identification.

Participants will already have been selected for stereoEEG and will undergo a supplementary MRI (about 1h) with the additional MRI sequences. Follow-up MRI are scheduled for patient undergoing a second, therapeutic epileptic surgery.

Inclusion: Patient suffering from drug-resistant epilepsy; Patient already selected for SEEG implantation as part of their epileptic networks.

Exclusion: Patient excluded from SEEG (pregnant women, children too young for the procedure, patient unable to undergo the procedure); Contra-indication for MRI.

ClinicalTrials.gov NCT06059157