Advanced MRI to map brain networks in drug-resistant epilepsy
Tests advanced MRI scans to find seizure networks in people with drug-resistant epilepsy.
Key facts
- Who runs it
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Where
- Brussels, BelgiumSee the site
- Trial code
- Registry title
- Epileptogenic Network Visualisation With Advanced MRI
- Status
- Recruiting
- People taking part
- 80 people, planned
- Started
- 25 Oct 2023
- Expected to end
- Oct 2029
- Type of study
- Interventional
- Treatments tested
- Advanced MRI
- Record updated
- 15 June 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with epilepsy that does not respond to medicines. They must already be chosen for stereo-EEG, a test with electrodes placed in the brain. They will have an extra MRI scan of about 1 hour.
- Age
- From 3 years old.
- Sex
- Women and men can join.
- Disease stage
- Drug-resistant epilepsy.
- Earlier treatment
- Already selected for stereo-EEG (SEEG) implantation as part of their epileptic networks.
Main reasons for not taking part
- Excluded from SEEG (for example pregnant women, children too young, people unable to undergo the procedure)
- Contra-indication for MRI
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Patient suffering from drug-resistant epilepsy
- Patient already selected for SEEG implantation as part of their epileptic networks
Who cannot take part
- Patient excluded from SEEG (pregnant women, children too young for the procedure, patient unable to undergo the procedure)
- Contra-indication for MRI
Where in Belgium
- Cliniques Universitaires St-LucBrussels, BelgiumContact: Riëm El Tahry, PhDTaking people
About the trial
What the trial wants to find out
The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient.
Read full original descriptionShow less
The investigators aim to compare epileptogenic network identification with stereo-EEG (used as glod standard) with the identification of the same network using advanced MRI (rs-fMRI, microstructural analysis of white matter, ...). The main goals are to:
1. Compare the accuracy of network identification. 2. Analyse the effect of the MRI sequences on candidates selection and target identification.
Participants will already have been selected for stereoEEG and will undergo a supplementary MRI (about 1h) with the additional MRI sequences. Follow-up MRI are scheduled for patient undergoing a second, therapeutic epileptic surgery.
The group in the trial
- Single ArmTreatment being tested
Treatment: Advanced MRI
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Epileptogenic Network Visualisation With Advanced MRI
- Plain-language title
- Advanced MRI to map brain networks in drug-resistant epilepsyGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 15 June 2026