Adding light-activated therapy to gum cleaning in adults with obesity and gum disease
Tests an added light-activated treatment with gum cleaning in adults with obesity and periodontitis.
Plain-language title generated from the registry record
Registry title: Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity
Key facts
- Where
- Bauru, BrazilSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT06073704, who can take part
Where in Brazil
- Bauru School of DentistryBauru, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Sao Paulo
- Trial code
- NCT06073704
- Record updated
- 4 May 2026
- Original description
The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.Read full original descriptionShow less
Effects of Antimicrobial Photodynamic Therapy in Non-surgical Periodontal Treatment of Patients With Obesity
The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.
Inclusion: Obesity (grade II and III classified according to Body Mass Index); Periodontitis stage II to IV; Presence of at least 20 teeth excluding 3rd molars.
Exclusion: Alcohol or drugs consumption; Use of drugs that alter periodontal structures as phenytoin or ciclosporin; Kidney disorders; Smokers; Pregnancy or lactation; Use of antibiotics at the last 30 days; Periodontal treatment at the last 6 months.