Comparing two surgeries for thumb base osteoarthritis (rhizarthrosis)
Compares a thumb joint prosthesis with removal of a small wrist bone in rhizarthrosis.
Key facts
- Who runs it
- Clinique Bizet
- Where
- Paris, FranceSee the site
- Trial code
- Registry title
- Rhizarthrosis Surgery and Functional Recovery: Arthroplasty vs. Trapezectomy
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 24 Nov 2023
- Expected to end
- Dec 2028
- Type of study
- Observational, 2 groups
- Treatments tested
- HORUS
- Record updated
- 10 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with painful arthritis at the base of the thumb (rhizarthrosis) when non-surgical treatment has not worked. It compares a joint prosthesis with removal of the trapezium bone.
- Age
- Over 45 years, up to 85 years
- Sex
- All
- Disease stage
- Arthritis of the thumb base joint (trapezius-metacarpal osteoarthritis) that causes symptoms.
- Earlier treatment
- Non-surgical treatment must have failed: a night splint for 3 months and 2 failed injections per year.
Main reasons for not taking part
- Trapezium bone height < 8 mm
- Known allergy to the materials of the device
- Infection, dead skin or an unhealed wound at the hand
- Pregnant or breastfeeding women
- Adults under legal protection, curatorship or guardianship; also people taking part in another clinical study
The registry criteria, word for word
Show all 13 criteriaShow less
Who can take part
- Age >45 years
- Symptomatic trapezius-metacarpal osteoarthritis after failure of medical treatment ( night orthosis 3 months + failure of 2 infiltrations/year)
- Patient who has given his/her consent to participate in the study after being informed by the surgeon,
- Patient living in France and able to answer the survey alone
- Subject affiliated to a social security system or beneficiary of such a system
- No participation in any other clinical study
Who cannot take part
- Known allergy to the materials of the medical device
- Local infection
- Minor patient
- Trapezium height < 8 mm
- Major subject protected by law, under curatorship or guardianship
- Local skin necrosis or unhealed wound
- Pregnant or nursing women
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 45 and 85 years old?
Where in France
- Clinique BizetParis, FranceContact: Bouchra BENKESSOU, MPTaking people
About the trial
What the trial wants to find out
Rhizarthrosis is a form of osteoarthritis that affects the trapeziometacarpal joint at the base of the thumb, which is more common in women over 50. Genetic and hormonal factors as well as the frequency of certain physical movements may contribute to its appearance. Surgical treatment is recommended if medical treatment fails, and trapezectomy is currently considered the standard method, although 3rd generation trapeziometacarpal prostheses are also available.
Read full original descriptionShow less
The aim of this study is to compare the clinical and radiographic results after surgical treatment of rhizarthrosis: prosthesis versus trapezectomy.
The 2 groups in the trial
- Control
Trapezectomy group
- Experimental
Arthroplasty group
Treatment: HORUS
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Comparing Short-Term Functional Recovery After Surgery for Rhizarthrosis: Arthroplasty vs. Trapezectomy - A Prospective Randomized Evaluation
- Plain-language title
- Comparing two surgeries for thumb base osteoarthritis (rhizarthrosis)Generated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Fit questions
- Built from NCT06078189, who can take part
- Record updated
- 10 September 2026