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Wrist Denervation Vs Exercise in Wrist Osteoarthritis

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Trial details

Who runs it
Karolinska Institutet
Trial code
NCT06098586
Record updated
21 February 2025
Original description
A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.Read full original descriptionShow less

Partial Wrist Denervation Versus Self-managed Exercise Therapy in Patients with Wrist Osteoarthritis: a Randomized Controlled Multicenter Trial

A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.

Inclusion: Age ≥ 18 years; Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis; Radiological signs of osteoarthritis on posteroanterior and lateral radiograph.

Exclusion: Previous PIN or AIN neurectomy; Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment; Ongoing infection; Rheumatoid arthritis or other chronic inflammatory arthritis; Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints; Inability to co-operate with the follow-up protocol.

ClinicalTrials.gov NCT06098586