NCT06112327Enrolling by invitation
Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
Long-term Follow-up Study of Investigational Gene-editing Therapies in Participants With or at High Risk for Cardiovascular Disease
Source: ClinicalTrials.gov · Last updated 8 Apr 2026
Brief summary (registry, in English)
LTF-001 is a long-term follow-up study of participants who received an investigational gene-editing therapy developed by the sponsor to evaluate the long-term effects of the investigational therapy. Participants will be followed for a total of 15 years after the first administration of the gene-editing therapy.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 116 (estimated)
- First submitted
- 12 Oct 2023
- Start date
- 9 Jun 2024
- Primary completion date
- Oct 2039
- Lead sponsor
- Verve Therapeutics, Inc.
- Diseases
- Familial hypercholesterolaemia
- NCT number
- NCT06112327
What you commit to
- Study type: Observational
- Planned participants: 116
- From 9 Jun 2024 to the primary completion date, Oct 2039
- 3 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- A participant has completed or discontinued from a Verve sponsored clinical study in which they received at least one dose of study drug.
- A participant has provided informed consent for LTF-001.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Study Center Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Clinical Study Center Coordinator of this site? Confirm its status | Auckland | New Zealand | Unknown status |
| Clinical Study Center Coordinator of this site? Confirm its status | Christchurch | New Zealand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.