Screening pregnant women for risk of placental problems in Finland
Checks how well a pre-eclampsia risk calculator predicts placental problems in pregnant women.
Plain-language title generated from the registry record
Registry title: PEPPI Study: Identification of Women at Risk for Placental Dysfunction
Key facts
- Where
- Oulu, FinlandSee the site
Where in Finland
- The Wellbeing Services County of North OstrobothniaOulu, FinlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Oulu University Hospital
- Trial code
- NCT06115122
- Record updated
- 5 August 2025
- Original description
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a Finnish general population.Read full original descriptionShow less
PEPPI Study: Identification of Women at Risk for Placental Dysfunction During the First and Third Trimesters of Pregnancy
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a Finnish general population.
Condition or disease: pre-eclampsia, intrauterine growth restriction, polycystic ovary syndrome
Inclusion: Pregnant (first trimester); Understands Finnish; ≥18 years; Signed informed consent; Participates in PEPPI-study (criteria above); Blood samples at first and third trimester of pregnancy; Permits blood sampling from the umbilical cord when the baby is born; Biological father to the child born for the mother who participated in PEPPI study; ≥18 years; Signed informed consent; Born to mother who participated in PEPPI study; Signed informed consent from parent(s); Signed informed consent from parent(s); Mother has blood samples taken at first and third trimester (iron status); Child has blood samples taken at birth and at 3 months of age.
Exclusion: Multiple pregnancy; Miscarriage/termination of the index pregnancy; No first trimester blood sampling; No first or third trimester blood sampling; No umbilical cord blood sample after baby is born; Fathers; Does not understand Finnish; Children; No consent from parent(s); Mother/father declines participation; No consent from parent(s); No blood samples from mother; No blood samples from child.
Mothers.