Compares two ways of examining colon cancer tissue after surgery
Compares European and Japanese lab methods for examining removed colon cancer tissue.
Plain-language title generated from the registry record
Registry title: CompariSon Between the EuroPeAn and Japanese pathologiCal InvEstigation for Colon Cancer (SPACE)
Key facts
- Where
- Moscow, RussiaSee the site
- Phase
- Phase 3
Where in Russia
- Clinic of coloproctology and minimally invasive surgeryMoscow, RussiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Russian Society of Colorectal Surgeons
- Trial code
- NCT06119867
- Record updated
- 17 August 2026
- Original description
In general, the European pathological examination method primarily relies on pathologists and does not require the involvement of surgeons. The Japanese pathological evaluation approach, on the other hand, involves the intervention of surgeons, particularly in the extraction of lymph nodes from fresh specimens and the assessment of specimen quality. Given that the Japanese pathological assessment method lacks systematic evaluation and there is currently no literature clearly demonstrating its diagnostic accuracy, the main objective of this study is to verify whether the diagnostic accuracy of the Japanese pathological investigation method is inferior to that of the European pathological evaluation method.Read full original descriptionShow less
Comparison Between the European and Japanese Pathological Investigation for Colon Cancer (SPACE)
In general, the European pathological examination method primarily relies on pathologists and does not require the involvement of surgeons. The Japanese pathological evaluation approach, on the other hand, involves the intervention of surgeons, particularly in the extraction of lymph nodes from fresh specimens and the assessment of specimen quality. Given that the Japanese pathological assessment method lacks systematic evaluation and there is currently no literature clearly demonstrating its diagnostic accuracy, the main objective of this study is to verify whether the diagnostic accuracy of the Japanese pathological investigation method is inferior to that of the European pathological evaluation method.
Inclusion: Patients diagnosed with colon cancer who underwent colectomy; Patients with pathological confirmed adenocarcinoma; Patients agreed to participate in the study.
Exclusion: Patients suffered from rectal cancer; Patients diagnosed with colon cancer but did not undergo colectomy; Patients refused participation.