Building 3D Lab Models of Pancreatic Neuroendocrine Tumours From Patient Tissue
Builds personal 3D lab models from surgical tissue of adults with pancreatic tumours.
Plain-language title generated from the registry record
Registry title: Development of New Personalised 3D Preclinical Models of Pancreatic Neuroendocrine Tumours
Key facts
- Where
- Milan, ItalySee the site
Where in Italy
- IRCCS San Raffele InstituteMilan, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- IRCCS San Raffaele
- Trial code
- NCT06121622
- Record updated
- 1 May 2025
- Original description
The goal of this prospective observational study is to generate new personalised 3D preclinical models of pancreatic neuroendocrine tumors. The models will be exploited for studying the mechanisms underlying disease development and progression, as well as for performing drug testing. For the development of the newly proposed models, patients' surgical specimens will be evaluated by the Pathological Unit. If the presence of pathological material in excess, not required for the routine diagnostic procedure, is confirmed, such material will be employed for the generation of the proposed personalised models.Read full original descriptionShow less
Development of New Personalised 3D Preclinical Models of Pancreatic Neuroendocrine Tumours
The goal of this prospective observational study is to generate new personalised 3D preclinical models of pancreatic neuroendocrine tumors. The models will be exploited for studying the mechanisms underlying disease development and progression, as well as for performing drug testing. For the development of the newly proposed models, patients' surgical specimens will be evaluated by the Pathological Unit. If the presence of pathological material in excess, not required for the routine diagnostic procedure, is confirmed, such material will be employed for the generation of the proposed personalised models.
Inclusion: patients who undergo pancreatic surgical resection for non-functioning pancreatic neuroendocrine tumor; age ≥ 18 years; informed consent.
Exclusion: age < 18 years; non-pancreatic neuroendocrine tumor histological diagnosis.