Tests hyperbaric oxygen therapy for optic nerve damage in adults
Tests hyperbaric oxygen against a sham treatment in adults with optic neuropathy.
Plain-language title generated from the registry record
Registry title: Hyperbaric Oxygen Therapy for Optic Neuropathies
Key facts
- Where
- Palo Alto, United StatesSee the site
Where in United States
- Byers Eye InstitutePalo Alto, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Stanford University
- Trial code
- NCT06128720
- Record updated
- 9 October 2026
- Original description
The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.Read full original descriptionShow less
A Randomized, Sham Controlled, Masked Phase II Study to Evaluate the Neuroprotective Effect of Hyperbaric Oxygen Therapy on Optic Neuropathy
The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.
Inclusion: Patients must meet all of the following criteria to join the study (all eligibility criteria must be met at the screening and baseline visits unless otherwise noted):; Participant must be at least 18; Participant must has the ability to comply with the requirements of the study and complete the schedule of events (SOE); Participant's with clinical evidence of optic neuropathy; Participant must understand and sign the informed consent. If the participant's vision is impaired to the point where he/she cannot read the informed consent document, the document will be read to the participant in its entirety.
Exclusion: Participant is currently participating in or has within the last 3 months participated in any other clinical trial of a drug by ocular (if in the study eye) or systemic administration; Participant abusing drugs or alcohol; Prior treatment with hyperbaric oxygen within the last 6 months; Participant has, in the opinion of the investigator, any physical or mental condition that would increase the risk of participation in the study or may interfere with the study procedures, evaluations and outcome assessments; Participant is unable to comply with study procedures or follow-up visits; Participant has evidence of corneal opacification or lack of optical clarity; Participant is pregnant or lactating; Children and comatose patients; Participant with claustrophobia or that cannot decompress properly.