Genetic testing of embryos before transfer in women with infertility
Tests genetic screening of embryos before single transfer in women with infertility.
Key facts
- Who runs it
- Genomic Prediction Inc.
- Where
- Waltham, United StatesSee the site
- Trial code
- Registry title
- GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial
- Status
- Recruiting
- People taking part
- 240 people, planned
- Started
- 15 Nov 2023
- Planned end
- 15 Nov 2026
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Preimplantation genetic testing for aneuploidy (PGTA)
- Record updated
- 26 August 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 35 to 40 having IVF who plan to transfer one embryo. It compares transferring an embryo tested for chromosome problems (PGT-A) with an untested embryo.
- Age
- 35 to 40 years at the start of the IVF cycle
- Sex
- Women only
- Disease stage
- Female infertility, undergoing IVF with any ovarian stimulation protocol
Main reasons for not taking part
- Using donor eggs or a gestational carrier (surrogate)
- 3 or more miscarriages in a row
- 3 or more failed embryo transfers
- Needing embryo testing for a single-gene disorder (PGT-M)
- Carrying a chromosome translocation
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Women undergoing IVF of between 35 and 40 years of age at IVF cycle start
- Utilization of Intracytoplasmic Sperm Injection ICSI (recommended) or ---Traditional IVF
- Utilization of ejaculated or testicular sperm
- Utilization of autologous or donor sperm
- All Controlled Ovarian Hyperstimulation (COH) protocols
Who cannot take part
- Recurrent Implantation Failure (RIF) defined as ≥ 3 more failed embryo transfers
- Preimplantation genetic testing for monogenic/single gene disorders (PGT-M)
- Utilization of donor oocytes
- Utilization of gestational carrier
- Recurrent Pregnancy Loss (RPL) defined as ≥ 3 consecutive miscarriages
- Translocation carriers
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 35 and 40 years old?
Where in United States
- Boston IVFWaltham, United StatesContact: Kristin RooneyTaking people
About the trial
What the trial wants to find out
The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40 years of age.
The 2 groups in the trial
- Experimental Arm - Transfer of Best Quality, Euploid BlastocystTreatment being tested
Transfer of best quality, PGTA normal (euploid) blastocyst.
Treatment: Preimplantation genetic testing for aneuploidy (PGTA)
- Control Arm - Transfer of Untested, Best Quality BlastocystNo study treatment, for comparison
Transfer of Untested, Best Quality Blastocyst
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial
- Plain-language title
- Genetic testing of embryos before transfer in women with infertilityGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 15 November 2026.
- Fit questions
- Built from NCT06141135, who can take part
- Record updated
- 26 August 2025