NCT06146335Completed
Analysis of Biologic Signatures in Crohn's Patients Undergoing Surgery
Source: ClinicalTrials.gov · Last updated 18 Nov 2025
Brief summary (registry, in English)
The purpose of this study is to compare the effect of two procedures - the Kono-S procedure and the side-to-side functional end to end anastomosis - on the microbiome (the bacteria that live in our gut) and on the intestinal immune system. The investigators are hypothesizing that there are differences in the microbiome environment and the immune environment between the two procedural groups.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 11 (actual)
- First submitted
- 17 Nov 2023
- Start date
- Jan 2024
- Primary completion date
- May 2025
- Lead sponsor
- Weill Medical College of Cornell University
- Diseases
- Crohn's disease
- NCT number
- NCT06146335
What you commit to
- Study type: Interventional
- Participants enrolled: 11
- From Jan 2024 to the primary completion date, May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients that may need a different surgical procedure as per the surgeon at the time of intraoperative evaluation
Age
- Patients under 18 years of age.
Other
- Pregnant patients.
- Patient does not speak English
Who the study is looking for
- Patients with Crohn's ileitis/ileocolitis requiring surgical resection OR patients previously enrolled in the "Kono-S anastomosis versus side-to-side functional end anastomosis in the prevention of post-operative recurrence of Crohn's Disease (WC IRB #1303013645)" trial.
- Patients age 18 years and older.
- All phenotypes will be included: nonstricturing nonpenetrating (B1), stricturing (B2), and penetrating (B3) according to the Vienna classification.
- Patients will be included regardless of preoperative medications (untreated, steroids, biologics)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Weill Cornell Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.