Glenohumeral Joint Contract Patterns in Osteoarthritic Glenoids
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- Who runs it
- Universitaire Ziekenhuizen KU Leuven
- Trial code
- NCT06154694
- Record updated
- 2 April 2026
- Original description
Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration.Read full original descriptionShow less
In-vivo Evaluation of Glenohumeral Joint Contact Patterns in Osteoarthritic Glenoids
Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration.
Total shoulder arthroplasty (TSA) has been shown to relieve the pain and improve joint function of patients with OA. However, several complications such as component loosening and polyethylene damage has been reported and it has been revealed that 7.3% of glenoids may show signs of asymptomatic radiographic loosening annually after primary anatomic TSA. The mechanism of such fixation failure is still unclear.
The main goal of this study is evaluating in-vivo glenohumeral contact patterns in patients with osteoarthritic glenoids before and after TSA, to unravel the high rate of glenoid component loosening.
Inclusion: OA patients group; Patients with glenohumeral osteoarthritis planned for anatomic shoulder arthroplasty in the University Hospitals Leuven, Belgium; Complete patient informed consent; Pain free at the time of EOS imaging; Healthy control group; Healthy adult volunteers with no history of shoulder pain or trauma; Confirmation of the physician, that subject's clinical evaluation and CT scan did not show any abnormalities; Complete informed consent; Revised TSA group; Patients with glenohumeral osteoarthritis who received an anatomic shoulder arthroplasty at the University Hospitals Leuven within the past 30 years, and who have been revised for loosening of the glenoid component; At least 1 postoperative CT scan available.
Exclusion: Only patients with a functional TSA will be included, so patients with postoperative stiffness, pain, instability or pseudoparalysis will be excluded.