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Comparing two emotion-regulation therapies for autistic youth and young adults

Compares two emotion-regulation programs in autistic people aged 10 to 30.

Plain-language title generated from the registry record
Registry title: Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults

Key facts

Where
Pittsburgh and Tuscaloosa, United StatesSee the 2 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 10 and 30 years old?

Source: NCT06158581, who can take part

Where in United States

  • University of PittsburghPittsburgh, United StatesTaking people
  • University of AlabamaTuscaloosa, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of Pittsburgh
Trial code
NCT06158581
Record updated
13 April 2026
Original description
Too few clinicians are able and willing to help autistic patients. A recent review identified challenges to mental health service delivery in autism, including a lack of interventions designed for community implementation and limited workforce capacity. It has been argued that improving impairment in emotion regulation has the potential to improve a range of mental health difficulties in autistic people. In this clinical trial, the investigators are comparing two evidence-based interventions for emotion regulation, to determine if one created specifically for autistic people is clinically superior. The interventions will be implemented in the community, through partnering agencies.Read full original descriptionShow less

The Emotion Awareness and Skills Enhancement (EASE) Program Versus the Unified Protocol (UP)

Too few clinicians are able and willing to help autistic patients. A recent review identified challenges to mental health service delivery in autism, including a lack of interventions designed for community implementation and limited workforce capacity. It has been argued that improving impairment in emotion regulation has the potential to improve a range of mental health difficulties in autistic people. In this clinical trial, the investigators are comparing two evidence-based interventions for emotion regulation, to determine if one created specifically for autistic people is clinically superior. The interventions will be implemented in the community, through partnering agencies.

Inclusion: professional diagnosis of ASD; a score in the clinical range on the EDI-Reactivity or EDI-Dysphoria scale based on caregiver report or self-report; The study is open to people with a range of communication abilities. Participants must be able to consent to the study themselves and answer questions about themselves; Participants need to have a support person that could answer questions about them too. This could be a parent, caregiver, family member, partner or friend. Independent adults can opt out of this portion; Participants must live in Alabama or Pennsylvania.

Exclusion: Higher level of care is needed (Imminent Suicide / Homicide Threat, acute psychosis, mania).

ClinicalTrials.gov NCT06158581