NCT06165289Enrolling by invitation
Endoscopic Balloon Dilatation Combined With PRP Injection in Colonic Stenosis in Crohn's Disease
Efficacy and Safety of Endoscopic Balloon Dilatation Combined With Autologous Platelet-rich Plasma (PRP) Injection in Colonic Stenosis in Crohn's Disease
Source: ClinicalTrials.gov · Last updated 14 Jan 2026
Brief summary (registry, in English)
The aim was to investigate whether endoscopic balloon dilatation combined with PRP injection can help prevent or prolong restenosis in patients with Crohn's disease with colonic stenosis, and to explore the concentration of PRP. The study was a single-center, randomized, non-controlled study. Experimental group of patients underwent endoscopic balloon dilation and submucosal injection of PRP at the wound edge, historical control was used, and the patients included in the study were randomly divided into high concentration group and low concentration group.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 74 (estimated)
- First submitted
- 1 Dec 2023
- Start date
- 1 Mar 2024
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
- Diseases
- Crohn's disease
- NCT number
- NCT06165289
What you commit to
- Study type: Interventional
- Planned participants: 74
- From 1 Mar 2024 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- The patient has contraindications for endoscopic therapy, such as coagulation disorder, severe cardiopulmonary dysfunction, active bleeding, and inability to cooperate.
- Deep and large active ulcer was found in the stenosis;
- \< 18 years old;
- Foreign patients;
- Patients with a history of malignant tumors, including melanoma (except local skin cancer);
- Pregnant or nursing patients;
- Patients who could not be followed at all nodes of the primary outcome indicator; Other diseases that researchers believe could put patients at risk;
- Other diseases that researchers believe could put patients at risk.
Who the study is looking for
- Diagnosed as CD;
- Stenosis of the colon was found during colonoscopy, and surgery was not considered for the time being; ③ Narrow length \<5cm; ④ The patients agreed to undergo endoscopic balloon dilatation and voluntarily signed the informed consent to participate in this study, and were capable of complying with the agreement.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Sixth Affiliated Hospital, Sun Yat-sen University Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.