Tests exercise training in people with lupus
Tests high-intensity interval and resistance training in adults with systemic lupus erythematosus.
Plain-language title generated from the registry record
Registry title: Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
Key facts
- Where
- Stockholm, SwedenSee the site
Where in Sweden
- Carina BoströmStockholm, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Karolinska Institutet
- Trial code
- NCT06166199
- Record updated
- 12 December 2023
- Original description
The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosusRead full original descriptionShow less
Effects of High-intensity Interval Training Combined With Resistance Training in Patients With Systemic Lupus Erythematosus
The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosus
Inclusion: ≥18 years old; Fulfilment of the 1982 American College of Rheumatology (ACR) criteria; or 2012 Systemic Lupus International Collaborating Clinics (SLICC/ACR-Damage Index (DI)) classification criteria; or EULAR/ACR criteria; or patients that have received the diagnosis SLE on clinical grounds; Low to moderate disease activity, for example defined as a score of ≤5 in the clinical version of the SLE Disease Activity Index 2000 (SLEDAI-2K), i.e., excluding the serological descriptors (anti-dsDNA positivity and low complement levels); Low/minimal or no organ damage, for example defined as a score of ≤3 in the SLICC/ACR DI; Stable pharmacological treatment; The ability to perform a maximal ergometercycle exercise test; Be able to read and understand Swedish.
Exclusion: Symptoms or signs of cerebro-vascular disease, pulmonary embolus, pulmonary hypertension, pulmonary fibrosis, cardiovascular disease, angina pectoris, myocardial infarction, dyspnea at rest, uncontrolled blood pressure and uncontrolled diabetes within one year prior to study entry. Chronic kidney disease with; Patients who fulfil the absolute contraindications for maximal exercise testing according to American Heart Association; Patients who cannot perform a maximal ergometercycle exercise test due to the disease; Diseases or other conditions that strongly reduce the ability to exercise or that exercise is not recommended; Patients who perform regular aerobic fitness training and muscle strength exercise sessions at fixed times, >1 time/week; Pregnancy.