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Observing Breathing Machine Settings in Children Having General Anesthesia

Studies how children under 16 are ventilated during surgery and lung complications afterward.

Plain-language title generated from the registry record
Registry title: Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia

Key facts

Where
Amsterdam, NetherlandsSee the site

Where in Netherlands

  • Amsterdam University Medical CentersAmsterdam, NetherlandsTaking people

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Trial details

Who runs it
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Trial code
NCT06166706
Record updated
9 April 2025
Original description
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.Read full original descriptionShow less

Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia and Associations With Postoperative Pulmonary Complications - a Multicenter Prospective Cohort Study

Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.

Inclusion: aged ≤ 16 years; undergoing general anesthesia; airway management with tube or LMA; and; connected to mechanical ventilator . minimum duration of procedure: 15 minutes.

Exclusion: patients undergoing surgical procedures involving extra-corporal circulation; patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation; sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and; (rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.

ClinicalTrials.gov NCT06166706