Studying mitochondria in women with PCOS, insulin resistance and infertility
Observes mitochondrial changes in women aged 20 to 45 with polycystic ovary syndrome.
Plain-language title generated from the registry record
Registry title: Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Key facts
- Where
- Budapest, HungarySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 45 years old?
Source: NCT06167135, who can take part
Where in Hungary
- Semmelweis UniversityBudapest, HungaryTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Semmelweis University
- Trial code
- NCT06167135
- Record updated
- 18 December 2023
- Original description
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.Read full original descriptionShow less
Polycystic Ovary Syndrome, Insulin Resistance, Infertility, Obesity, and the Associated Mitochondrial Dysfunction With These Disorders in Hungarian Patients
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.
During the research biomarkers already with mitochondrial dysfunction in the scientific literature and common mtDNA abnormalities (deletions, point mutations, copy number changes, etc.) are examined.
Inclusion: Presence of polycystic ovary syndrome (PCOS) or insulin resistance (IR) associated with other multisystemic phenotypes, mitochondrial dysfunction; history of infertility associated with other multisystemic phenotypes, mitochondrial dysfunction; a known history of mitochondrial dysfunction and PCOS and/or IR; general health is good and there is no serious general medical condition that would prevent participation would make participation highly risky.
Exclusion: poor cooperation; refusal to participate in the study.