Testing beetroot extract for hard-to-control high blood pressure
Tests beetroot extract against a placebo in adults with resistant high blood pressure.
Plain-language title generated from the registry record
Registry title: Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Key facts
- Where
- Rio de Janeiro, BrazilSee the site
- Phase
- Early phase 1
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT06169241, who can take part
Where in Brazil
- National Institute of CardiologyRio de Janeiro, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Institute of Cardiology, Laranjeiras, Brazil
- Trial code
- NCT06169241
- Record updated
- 13 April 2026
- Original description
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.Read full original descriptionShow less
Effect of Nitrate Supplementation on Blood Pressure and Systemic Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.
Inclusion: Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days.
Exclusion: use of medications with nitrate in their formula; heart failure; neoplasms; patients undergoing renal denervation.