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Measures lung blood volume during exercise using contrast echocardiography ultrasound

Studies lung blood volume during exercise in adults with heart failure or lung vessel disease.

Plain-language title generated from the registry record
Registry title: Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume

Key facts

Where
Rochester, United StatesSee the site

Where in United States

  • Mayo Clinic in RochesterRochester, United StatesTaking people

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Trial details

Who runs it
Mayo Clinic
Trial code
NCT06195059
Record updated
20 August 2026
Original description
The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.Read full original descriptionShow less

Assessment of Pulmonary Blood Volume Using Contrast Echocardiography During Exercise

The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.

Inclusion: Patients referred to the cardiac catheterization laboratory for invasive exercise right heart catheterization for evaluating exertional dyspnea. Investigators will include patients with normal or low EF, and across the spectrum of pulmonary hypertension severity.

Exclusion: Prior adverse reaction to echo contrast administration; Patient inability or unwillingness to undergo echocardiography including a contrast method, or if echocardiography would, in the opinion of the investigator, somehow compromise the quality of data acquisition for the clinical case.

ClinicalTrials.gov NCT06195059