Combined memory training and exercise for memory in multiple sclerosis
Tests memory training with exercise in adults with multiple sclerosis and mobility problems.
Plain-language title generated from the registry record
Registry title: A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis
Key facts
- Where
- East Hanover, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT06197685, who can take part
Where in United States
- Kessler FoundationEast Hanover, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Kessler Foundation
- Trial code
- NCT06197685
- Record updated
- 5 August 2026
- Original description
The goal of this novel study is to compare the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory (NLM) in persons with multiple sclerosis (pwMS) and mobility disability.Read full original descriptionShow less
A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis
The goal of this novel study is to compare the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory (NLM) in persons with multiple sclerosis (pwMS) and mobility disability.
Inclusion: Be within the ages of 18 and 70 years of age; Speak English as their primary language; Confirmed MS diagnosis by a neurologist; Be relapse and steroid-free for at least 30 days; Mild-to-moderate self-reported mobility disability, based on the Patient Determined Disease Steps scale (PDDS); Currently physically inactive, based on the Godin Leisure Time Exercise Questionnaire (GLTEQ); Right handedness.
Exclusion: Currently use medications that may impact cognition (ex: steroids, benzodiazepines); History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression); Severe cognitive impairment as measured by the Modified Telephone Interview of Cognitive Status (TICS-M); Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q); Currently pregnant; Contraindication for MRI (metal or electronic devices in the body that are not considered MRI safe).